Catalog Number - 70200-10P-3

Unlock Superior Performance with Cogent Diamond Hydride 2.o HPLC Columns!

The 70200‑10P‑3 Diamond Hydride 2.0 HPLC Column is a solvent‑saving HILIC column configuration, specifically designed for laboratories seeking to reduce mobile phase consumption without sacrificing chromatographic performance or selectivity.

Why the 3.0 mm ID Matters

The 3.0 mm internal diameter places this column squarely between traditional 4.6 mm analytical columns and narrower LC‑MS‑only formats. Compared to a 4.6 mm ID column, this 3.0 mm “solvent saver” format:

• Uses approximately 55–60% less mobile phase

• Operates at lower optimal flow rates

• Generates reduced back pressure

• Delivers comparable run times and resolution, without requiring UHPLC hardware

This makes the column especially attractive for laboratories running high‑volume HILIC or LC‑MS methods, where solvent costs, waste disposal, and system wear are meaningful operational concerns.

Diamond Hydride 2.0 Performance Advantages

Built on Cogent TYPE‑C™ silica hydride technology, the Diamond Hydride 2.0 stationary phase offers:

• Fast equilibration, reducing downtime between HILIC runs

• Excellent retention and selectivity for polar and moderately polar analytes

• Improved control over mixed‑mode mechanisms common in HILIC separations

This makes the column well suited for:

• Polar and non‑polar peptides

• Amino acids

• Metabolites and small biomolecules

• Other challenging compounds analyzed via HILIC

Ideal for LC‑MS Workflows

The reduced flow requirements of the 3.0 mm ID format align naturally with LC‑MS and LC‑MS/MS systems, helping improve ionization efficiency while controlling solvent load entering the mass spectrometer.

Efficient by Design

This column offers a practical balance between analytical robustness and operational efficiency, allowing laboratories to:

• Maintain familiar HPLC‑scale workflows

• Reduce operating costs

• Avoid the need for specialized UHPLC systems

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